In animal copy scientific tests, codeine administered through the oral path to pregnant rats in the course of the period of organogenesis enhanced resorptions and reduced fetal weights in a dose around 26 moments the most encouraged human dose (MRHD) in the presence of maternal toxicity (see Info). For pregnant mice and rats that received promethazine at doses 0.05 to 6 periods the MRHD, during several durations of gestation, there have been findings of increased fetal resorptions and skeletal fragility, diminished pup excess weight, and developmental delays of pups (see Information). Based upon the animal data, suggest Expecting women on the potential threat to the fetus.
Promethazine with Codeine Oral Solution contains promethazine, a phenothiazine. Phenothiazines are connected with dystonic reactions, especially in pediatric people who have an acute ailment related with dehydration.
This medication can dry up and thicken mucus within your lungs, making it harder to breathe and distinct your lungs. To help stop this effect, consume a lot of fluids unless otherwise directed by your physician.
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Get crisis medical help In case you have hives; hard respiratory; swelling of one's facial area, lips, tongue, or throat. signs of an allergic reaction:
Use other supportive measures (like oxygen and vasopressors) while in the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require advanced life-assist tactics. Gastric emptying could be valuable in removing unabsorbed drug.
Small children are at better risk for major (even fatal) side effects, Specifically respiration issues. Communicate with the medical doctor with regard to the dangers and benefits of this medication.Cough-and-chilly products never treatment colds. Cough as a result of a common chilly typically will not need to be addressed with medication. Request your physician or pharmacist about other ways To ease cough and cold symptoms, for instance consuming enough fluids, employing a humidifier, or saline nose get more info drops/spray.
Given that Promethazine VC with Codeine is utilised when wanted, you may not be on the dosing timetable. Skip any skipped dose if It really is Nearly time on your following dose. Will not use two doses at a single time.
If a patient requires a refill, reevaluate the reason for the cough and evaluate the need for ongoing remedy with Promethazine with Codeine Oral Resolution, the relative incidence of adverse reactions, and the event of habit, abuse, or misuse.
Never ever share opioid medicine with One more individual, Specially an individual with a history of drug abuse or dependancy. MISUSE May cause Habit, OVERDOSE, OR DEATH. Preserve the medication in an area the place Other people are unable to reach it. Selling or giving away opioid drugs is against the law.
Employ other supportive measures (such as oxygen and vasopressors) inside the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias would require Superior daily life-guidance approaches. Gastric emptying may very well be useful in removing unabsorbed drug.
Tend not to maintain leftover medication. Only one dose might cause death in an individual making use of this drugs accidentally or improperly. Browse and thoroughly follow the Guidance offered with this medication regarding how to safely and securely get rid of any unused part.
Hemodialysis is just not routinely applied to boost the elimination of codeine or promethazine from the body.
When employed for an prolonged time, this medication may well not work also and will call for distinctive dosing. Talk with your medical doctor if this medication stops Performing perfectly.